Episode 54 – He built cancer surgery. Then told us to stop.

Dr. Charles Balch, professor emeritus at MD Anderson Cancer Center, helped make surgical oncology a specialty, led ASCO, and now runs ISOPT, the International Society of Oncology Prevention and Treatment. On this episode of Kicking Cancer's Ass, he tells Joelle Kaufman why the future of cancer care is prevention and early detection, not bigger surgery.

They cover how immunotherapy works (and why it treats the immune system, not the tumor), how six weeks of treatment now clears most stage 3 melanoma without an operation, and why cancer is rising fast in people under 50 who fall outside standard screening guidelines. Balch explains the difference between immunotherapy and chemotherapy, the link between obesity, processed food, vaping and cancer risk, and why a simple FIT test, an AI-enhanced mammogram, or affordable genetic (NGS) testing can catch disease while it's still curable.

If you or someone you love has been told “you're too young,” has a family history of breast, colorectal, or melanoma cancer, or wants to understand personalized risk and screening, this conversation is a practical, hopeful roadmap. Balch's advice comes down to three words: know your risk.

In this episode, they dive into:

  • Know your risk: family history, lifestyle, genes
  • Why “early” cancer isn't early: the billion-cell dime
  • Age-based screening is missing younger patients
  • Immunotherapy that treats you, not the tumor
  • Stage 3 melanoma cleared without a scalpel
  • The cheap FIT test your doctor skips
  • New blood tests: promise, and their limits
  • Why knowing your risk is a gift, not a sentence

You're not done. That's not a failure. The calendar is yours.

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Zoe Gonzalez

Zoe Gonzalez

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